Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

335 questions · 350 findings · 37 reviews

No studies found 69 · 19.7%GRADE not reported 45 · 12.9%Very low 92 · 26.3%Low 114 · 32.6%Moderate 30 · 8.6%High 0 · 0%

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Relapse · people with both severe mental illness and substance misuse

It is very uncertain whether cognitive behavioural therapy + motivational interviewing changes relapse:* Relapse at 3 months after 9 months of treatment compared with standard care (very low certainty).

1 finding from 1 review