Findings

What do systematic reviews say?

11 questions · 11 findings · 2 reviews

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No studies found 5 · 45.5%GRADE not reported 0 · 0%Very low 6 · 54.5%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Citalopram vs placebo

Participant‐reported pain relief of 30% or greater · children (4 to 18 years) with functional abdominal pain disorders

The review found no eligible studies for this question.

1 finding from 1 review

Antidepressants for chronic non‐cancer pain in children and adolescents 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Citalopram vs placebo

Participant‐reported pain relief of 50% or greater · children (4 to 18 years) with functional abdominal pain disorders

The review found no eligible studies for this question.

1 finding from 1 review

Antidepressants for chronic non‐cancer pain in children and adolescents 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Citalopram vs placebo

Patient Global Impression of Change much or very much improved · children (4 to 18 years) with functional abdominal pain disorders

The review found no eligible studies for this question.

1 finding from 1 review

Antidepressants for chronic non‐cancer pain in children and adolescents 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Citalopram vs placebo

Adverse events · children (4 to 18 years) with functional abdominal pain disorders

1 finding from 1 review

Antidepressants for chronic non‐cancer pain in children and adolescents 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 115 participants
Very low

Citalopram vs placebo

Serious adverse events · children (4 to 18 years) with functional abdominal pain disorders

1 finding from 1 review

Antidepressants for chronic non‐cancer pain in children and adolescents 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 115 participants
Very low

Citalopram vs placebo

Withdrawals due to adverse events · children (4 to 18 years) with functional abdominal pain disorders

1 finding from 1 review

Antidepressants for chronic non‐cancer pain in children and adolescents 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 115 participants
Very low

Escitalopram vs placebo

Severity of PTSD symptoms ‐ Clinician‐rated · adults experiencing acute traumatic stress symptoms

1 finding from 1 review

Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 23 participants
Very low

Escitalopram vs placebo

Dropouts due to adverse events · adults experiencing acute traumatic stress symptoms

1 finding from 1 review

Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Very low

Escitalopram vs placebo

PTSD rate at 3 months · adults experiencing acute traumatic stress symptoms

It is very uncertain whether escitalopram changes PTSD rate at 3 months compared with placebo (very low certainty).

1 finding from 1 review

Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… 2024 · Cochrane Headline outcomes only
RR 0.59 [0.03, 13.08]
1 study · 23 participants
Very low

Escitalopram vs placebo

Functional disability at 3 months ‐ not measured · adults experiencing acute traumatic stress symptoms

The review found no eligible studies for this question.

1 finding from 1 review

Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Escitalopram vs placebo

Quality of life at 3 months ‐ not measured · adults experiencing acute traumatic stress symptoms

The review found no eligible studies for this question.

1 finding from 1 review

Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found