Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Dental caries

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No studies found 1 · 20%GRADE not reported 2 · 40%Very low 2 · 40%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Chlorhexidine varnish vs placebo or no treatment

Adverse events (e.g. ulcers, tooth staining) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

1 finding from 1 review

Chlorhexidine treatment for the prevention of dental caries in children and adolescents 2015 · Cochrane All outcomes
One study reported no adverse events for ulcers or tooth staining. One study stated "side-effects due to the CHX treatment were not noted".
2 studies
GRADE not reported

Chlorhexidine varnish vs placebo or no treatment

Pain, quality of life, patient satisfaction or costs · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

The review found no eligible studies for this question.

1 finding from 1 review

Chlorhexidine treatment for the prevention of dental caries in children and adolescents 2015 · Cochrane All outcomes
No trials reported on pain, quality of life, patient satisfaction or costs.
0 studies
No studies found

Chlorhexidine varnish (10%) vs placebo or no treatment

Elevated mutans streptococci levels (>=4 with caries screen; high vs low) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

It is very uncertain whether chlorhexidine varnish (10%) changes elevated mutans streptococci levels (>=4 with caries screen; high vs… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Chlorhexidine treatment for the prevention of dental caries in children and adolescents 2015 · Cochrane All outcomes
6 to 36 months · permanent dentition
RR 0.93 [0.80, 1.07]
1 study · 496 participants
Very low

Chlorhexidine varnish (10% and 40%) vs placebo or no treatment

Caries increment in permanent teeth · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

It is very uncertain whether chlorhexidine varnish (10% and 40%) changes caries increment in permanent dentition (DMFS; higher values… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Chlorhexidine treatment for the prevention of dental caries in children and adolescents 2015 · Cochrane All outcomes
30 to 36 months · permanent dentition
MD 0.53 [-0.47, 1.53]
2 studies · 690 participants
Very low

Chlorhexidine varnish vs placebo or no treatment

Dental caries: dmfs increment (primary teeth) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

1 finding from 1 review

Chlorhexidine treatment for the prevention of dental caries in children and adolescents 2015 · Cochrane All outcomes
24 months · primary dentition
Two trials with unit of analysis problem. Data imputations indicated no evidence to claim or refute a benefit
2 studies · 471 participants
GRADE not reported