What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Dental caries

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No studies found 1 · 25%GRADE not reported 1 · 25%Very low 2 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Chlorhexidine gel (0.12%) vs no treatment

Mutans streptococci prevalence (presence/absence) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

It is very uncertain whether chlorhexidine gel (0.12%) changes mutans streptococci prevalence (presence/absence) compared with no treatment (very low certainty).

1 finding from 1 review

Chlorhexidine treatment for the prevention of dental caries in children and adolescents 2015 · Cochrane All outcomes
24 months · primary dentition
RR 1.26 [0.95, 1.66]
2 studies · 490 participants
Very low

Chlorhexidine gel (0.12%) vs no treatment

Adverse events · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

1 finding from 1 review

Chlorhexidine treatment for the prevention of dental caries in children and adolescents 2015 · Cochrane All outcomes
24 months · primary dentition
Both studies reported there were no adverse events.
2 studies
GRADE not reported

Chlorhexidine gel (0.12%) vs no treatment

Pain, quality of life, patient satisfaction or costs · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

The review found no eligible studies for this question.

1 finding from 1 review

Chlorhexidine treatment for the prevention of dental caries in children and adolescents 2015 · Cochrane All outcomes
Neither of these trials reported on the other secondary outcomes such as measures of pain, quality of life, patient satisfaction or direct and indirect costs of interventions.
0 studies
No studies found

Chlorhexidine gel (0.12%) vs no treatment

Presence of new caries in the primary teeth · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

It is very uncertain whether chlorhexidine gel (0.12%) changes presence of new caries in the primary teeth compared with no treatment (very low certainty).

1 finding from 1 review

Chlorhexidine treatment for the prevention of dental caries in children and adolescents 2015 · Cochrane All outcomes
24 months · primary dentition
RR 1.00 [0.36, 2.77]
2 studies · 487 participants
Very low