Findings

What do systematic reviews say?

6 questions · 7 findings · 1 reviews · Headline outcomes only

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No studies found 0 · 0%GRADE not reported 2 · 28.6%Very low 2 · 28.6%Low 1 · 14.3%Moderate 2 · 28.6%High 0 · 0%

Children: higher dose/longer course vs lower dose/shorter course

Re‐admission during · children with acute asthma

1 finding from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 98 participants
Very low

Children: higher dose/longer course vs lower dose/shorter course

Asthma symptoms · children with acute asthma

Children: higher dose/longer course showed no clear difference in asthma symptoms Symptom free by 7 days compared with lower dose/shorter course (moderate certainty).

1 finding from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
OR 1.22 [0.67, 2.19]
1 study · 201 participants
Moderate

Children: higher dose/longer course vs lower dose/shorter course

Serious adverse events · children with acute asthma

1 finding from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 201 participants
GRADE not reported

Children: higher dose/longer course vs lower dose/shorter course

Exacerbations · children with acute asthma

Children: higher dose/longer course showed no clear difference in new exacerbation during compared with lower dose/shorter course (low certainty).

2 findings from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
OR 1.38 [0.25, 7.47]
2 studies · 231 participants
Low
Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
OR 2.17 [0.67, 7.01]
1 study · 100 participants
Very low

Children: higher dose/longer course vs lower dose/shorter course

FEV1 % predicted · children with acute asthma

1 finding from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
GRADE not reported

Children: higher dose/longer course vs lower dose/shorter course

All adverse events · children with acute asthma

Children: higher dose/longer course showed no clear difference in all adverse events compared with lower dose/shorter course (moderate certainty).

1 finding from 1 review

Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
OR 0.67 [0.11, 4.08]
1 study · 201 participants
Moderate