Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

31 questions · 31 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 4 · 12.9%Very low 25 · 80.6%Low 0 · 0%Moderate 2 · 6.5%High 0 · 0%

Irradiated carious dentin vs Non-irradiated carious dentin

MMP-20 expression · Human ex vivo carious dentin (head/neck radiotherapy)

MMP-20 shows no difference between irradiated and non-irradiated carious dentin; the evidence is very uncertain (very low certainty).

1 finding from 1 review

Carious dentin before cavity sealing vs Carious dentin after cavity sealing

MMP-8 expression/activity · Human ex vivo carious dentin under sealed cavities

MMP-8 may be higher before than after cavity sealing, but the evidence is very uncertain (very low certainty).

1 finding from 1 review

Carious dentin before cavity sealing vs Carious dentin after cavity sealing

MMP-9 expression/activity · Human ex vivo carious dentin under sealed cavities

MMP-9 shows no difference before vs after cavity sealing; the evidence is very uncertain (very low certainty).

1 finding from 1 review

Carious dentin before cavity sealing vs Carious dentin after cavity sealing

MMP-2 expression/activity · Human ex vivo carious dentin under sealed cavities

MMP-2 shows no difference before vs after cavity sealing; the evidence is very uncertain (very low certainty).

1 finding from 1 review

Outer carious dentin (by lesion depth/location) vs Inner carious dentin

MMP-8 location/depth · Human ex vivo carious dentin

MMP-8 showed no statistical difference by lesion location; the evidence is very uncertain (very low certainty).

1 finding from 1 review

Outer carious dentin (by lesion depth/location) vs Inner carious dentin

MMP-2 location/depth · Human ex vivo carious dentin

No clear direction of MMP-2 presence by lesion depth/location was found; the evidence is very uncertain (very low certainty).

1 finding from 1 review

Outer carious dentin (by lesion depth/location) vs Inner carious dentin

MMP-20 location/depth (outer vs inner) · Human ex vivo carious dentin

MMP-20 probably decreases in outer compared with inner carious dentin (moderate certainty).

1 finding from 1 review

Outer carious dentin (by lesion depth/location) vs Inner carious dentin

MMP-9 location/depth · Human ex vivo carious dentin

No clear direction of MMP-9 expression by lesion depth/location was found; the evidence is very uncertain (very low certainty).

1 finding from 1 review