Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 1 · 50%Very low 1 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

MMP-9 expression/activity · Human ex vivo carious dentin (head/neck radiotherapy)

MMP-9 showed no increase in irradiated vs non-irradiated carious dentin (one study; ungraded).

1 finding from 1 review

Presence of host and bacterial-derived collagenolytic proteases in carious dentin: a systematic review of ex vivo… 2023 All outcomes
Ex vivo (extracted teeth / clinical carious or biofilm samples)
MMP-9 predominantly positive in non-irradiated vs irradiated carious dentin (single study; ungraded)
1 study · 36 participants
GRADE not reported

MMP-9 expression/activity · Human ex vivo carious dentin under sealed cavities

MMP-9 shows no difference before vs after cavity sealing; the evidence is very uncertain (very low certainty).

1 finding from 1 review

Presence of host and bacterial-derived collagenolytic proteases in carious dentin: a systematic review of ex vivo… 2023 All outcomes
Before vs after sealing (Kuhn 2016: 60 days follow-up) · Ex vivo (extracted teeth / clinical carious or biofilm samples)
There is no difference of MMP-9 expression/activity before and after cavity sealing, although the evidence is very uncertain.
2 studies · 48 participants
Very low