Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews

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Carbamazepine vs phenytoin

Time to first seizure (post‐randomisation) ‐ stratified by epilepsy type: generalised onset seizures (tonic‐clonic only) Range of · adults and children with newly onset partial or generalised epilepsy

Carbamazepine showed no clear difference in time to first seizure after randomisationSubgroup: generalisedonset… compared with phenytoin (secondary outcomes) (low certainty).

1 finding from 1 review

Carbamazepine versus phenytoin monotherapy for epilepsy: an individual participant data review 2019 · Cochrane Headline outcomes only
HR 1.19 [0.81, 1.75]
3 studies · 150 participants
Low