Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Acute Respiratory Infections

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 100%Moderate 0 · 0%High 0 · 0%

Resolution of symptoms post‐treatment (ITT analysis) · group A streptococcal pharyngitis

Carbacephem may leads to lower resolution of symptoms post‐treatment (ITT analysis) compared with penicillin (low certainty).

1 finding from 1 review

Different antibiotic treatments for group A streptococcal pharyngitis 2023 · Cochrane Headline outcomes only
OR 0.7 [0.49, 0.99]
3 studies · 795 participants
Low

Resolution of symptoms post‐treatment (evaluable participants) · group A streptococcal pharyngitis

Carbacephem showed no clear difference in resolution of symptoms post‐treatment (evaluable participants) compared with penicillin (low certainty).

1 finding from 1 review

Different antibiotic treatments for group A streptococcal pharyngitis 2023 · Cochrane Headline outcomes only
OR 0.62 [0.38, 1.01]
3 studies · 602 participants
Low

Relapse · group A streptococcal pharyngitis

Carbacephem showed no clear difference in incidence of relapse (evaluable participants) compared with penicillin (low certainty).

1 finding from 1 review

Different antibiotic treatments for group A streptococcal pharyngitis 2023 · Cochrane Headline outcomes only
OR 1.27 [0.64, 2.5]
3 studies · 523 participants
Low

Adverse events (ITT analysis) · group A streptococcal pharyngitis

Carbacephem showed no clear difference in adverse events (ITT analysis) compared with penicillin (low certainty).

1 finding from 1 review

Different antibiotic treatments for group A streptococcal pharyngitis 2023 · Cochrane Headline outcomes only
OR 1.08 [0.75, 1.55]
3 studies · 795 participants
Low