Calcium phosphate agent (e.g., CPP-ACP, Ca/P-PILP, niobophosphate) vs Calcium-based agent
Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)
In the Etch-and-Rinse adhesive + chemical ACAD protocol network, Calcium Phosphate vs Calcium showed no significant difference in 24 h bond strength (MD 0.596, 95% CI -7.289 to 8.482; Low certainty).
2 findings from 1 review
- Biomimetic Remineralization Strategies for Dentin Bond Stability-Systematic Review and Network Meta-Analysis. 2025 All outcomes24 h (immediate) · In vitro; extracted permanent human teeth; bond strength testing (SBS/microSBS/microTBS) · Etch-and-Rinse + chemical ACADMD 0.596 [-7.289, 8.482]7 studiesLow
- Biomimetic Remineralization Strategies for Dentin Bond Stability-Systematic Review and Network Meta-Analysis. 2025 All outcomes24 h (immediate) · In vitro; extracted permanent human teeth; bond strength testing (SBS/microSBS/microTBS) · Self-Etch + chemical ACADMD 2.663 [-2.395, 7.722]4 studiesModerate