Overall success (composite of clinical and radiographic success) · Adults (>=18 y) with mature permanent teeth, carious exposure and normal/reversibly inflamed pulp
At 1 year, partial pulpotomy and direct pulp capping (both calcium hydroxide) gave similarly low success in reversibly inflamed pulps (34.5% vs 31.8%; ungraded, single trial).
2 findings from 1 review
Success rate (%) 34.5 vs 31.8
1 study · 51 participants
GRADE not reported
Success rate (%) 11.1 vs 5.9
1 study · 44 participants
GRADE not reported
Clinical symptoms at 12 months · Adults (aged 20 to 60 years, mean 27) with deep carious lesions in permanent teeth (indirect or direct pulp capping, or complete caries…
3 findings from 1 review
Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes12 months · Complete caries removal
Analysis 2.2 (clinical symptoms at 12 months following complete caries removal, Life vs Dycal). Fitzgerald 1991: 151 teeth in 55 patients (analysis at tooth level, not patient level); substantial attrition (11 teeth…
1 study · 151 participants
GRADE not reported
Analysis 2.1 (clinical symptoms at 12 months following indirect pulp capping, Life vs Dycal). Fitzgerald 1991: 151 teeth in 55 patients (analysis at tooth level, not patient level); substantial attrition (11 teeth lost…
1 study · 151 participants
GRADE not reported
Analysis 2.3 (clinical symptoms at 12 months following direct pulp capping, Life vs Dycal). Fitzgerald 1991: 151 teeth in 55 patients (analysis at tooth level, not patient level); substantial attrition (11 teeth lost…
1 study · 151 participants
GRADE not reported
Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure
Partial pulpotomy with calcium hydroxide had a pooled success rate of 34.3%.
1 finding from 1 review
Dentin bridge formation · Patients with carious pulp exposure in permanent teeth undergoing partial pulpotomy
Evidence on dentin bridge formation for calcium hydroxide versus MTA is weak and imprecise, with no material shown superior (4 RCTs, not pooled; ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in immature permanent teeth
In immature teeth, the effect of MTA versus calcium hydroxide on success is very uncertain (OR 2.22, 95% CI 0.13-36.67; very low certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing direct pulp capping
For direct pulp capping, MTA probably achieves higher clinical and radiographic success than calcium hydroxide (OR 3.10, 95% CI 1.66-5.79; moderate certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth of mixed/unspecified root maturation
In mixed-maturation teeth, the effect of MTA versus calcium hydroxide on success is very uncertain (OR 1.11, 95% CI 0.17-7.11; very low certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing pulpotomy
For pulpotomy, whether MTA improves success over calcium hydroxide is uncertain (OR 2.36, 95% CI 0.47-11.75; low certainty; CI includes no effect).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing DPC or pulpotomy
Biodentine appeared to perform better than calcium hydroxide for success, but the evidence was not pooled (2 RCTs; ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in mature permanent teeth
In mature teeth, MTA probably achieves higher clinical and radiographic success than calcium hydroxide (OR 3.34, 95% CI 1.81-6.17; moderate certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing DPC or pulpotomy
MTA achieved higher clinical and radiographic success than calcium hydroxide overall (OR 2.94, 95% CI 1.96-4.49; low certainty), but this unadjusted estimate pools clinically heterogeneous DPC and pulpotomy studies.
1 finding from 1 review
Continued root formation / root development · Patients with carious pulp exposure in permanent teeth (predominantly immature) undergoing DPC or pulpotomy
Evidence on continued root formation for calcium hydroxide versus MTA is weak and inconclusive (3 RCTs, not pooled; ungraded).
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Calcium hydroxide (CH) probably leads to higher radiological failure compared with formocresol (FC) (moderate certainty).
2 findings from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Calcium hydroxide (CH) may leads to higher clinical failure compared with formocresol (FC) (low certainty).
2 findings from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Calcium hydroxide (CH) showed no clear difference in radiological failure compared with ferric sulphate (FS) (low certainty).
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Calcium hydroxide (CH) showed no clear difference in clinical failure compared with ferric sulphate (FS) (low certainty).
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Calcium hydroxide (CH) showed no clear difference in clinical failure compared with portland cement (PC); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Calcium hydroxide (CH) showed no clear difference in clinical failure compared with mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl); GRADE not reported.
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Calcium hydroxide (CH) led to higher radiological failure compared with portland cement (PC); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Calcium hydroxide (CH) showed no clear difference in clinical failure compared with zinc oxide and eugenol (ZOE); GRADE not reported.
1 finding from 1 review