Findings

What do systematic reviews say?

64 questions · 73 findings · 3 reviews

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No studies found 1 · 1.4%GRADE not reported 56 · 76.7%Very low 2 · 2.7%Low 10 · 13.7%Moderate 4 · 5.5%High 0 · 0%

Calcium hydroxide cement (Dycal) vs Calcium sulphate hemihydrate (DentoGen)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether calcium hydroxide cement (Dycal) changes clinical failure compared with calcium sulphate hemihydrate (DentoGen) (very low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 4.00 [0.49, 32.72]
1 study · 40 participants
Very low

Calcium hydroxide cement (Dycal) vs Calcium sulphate hemihydrate (DentoGen)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether calcium hydroxide cement (Dycal) changes radiological failure compared with calcium sulphate hemihydrate (DentoGen) (very low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.67 [0.46, 6.06]
1 study · 40 participants
Very low

Calcium hydroxide (CH) vs Zinc oxide and eugenol (ZOE)

Clinical success (survival free of symptoms) at 24 months · Adults with asymptomatic teeth with vital carious pulp exposures

1 finding from 1 review

Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes
24 months
Shovelton 1971 (Analysis 1.1): 275 teeth followed for 2 years (235 at 6 months, 160 at 12 months, 85 analysed at 24 months). Success rates 50% to 80%. Ledermix and calcium hydroxide had the highest success rates,…
1 study · 275 participants
GRADE not reported

Vitapex (calcium hydroxide/iodoform) vs Calcium hydroxide (CH)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) showed no clear difference in radiological failure compared with calcium hydroxide (CH); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6 and 12 months
RR 0.11 [0.01, 1.94]
1 study · 40 participants
GRADE not reported

Vitapex (calcium hydroxide/iodoform) vs ZOE + calcium hydroxide + iodoform (MPRCF, unnamed product)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) led to higher radiological failure compared with ZOE + calcium hydroxide + iodoform (MPRCF, unnamed product); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 42.63 [2.65, 685.54]
1 study · 109 participants
GRADE not reported

Vitapex (calcium hydroxide/iodoform) vs Calcium hydroxide (CH)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with calcium hydroxide (CH); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 0.11 [0.01, 1.94]
1 study · 40 participants
GRADE not reported

Vitapex (calcium hydroxide/iodoform) vs Sealapex (eugenol-free calcium hydroxide)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) showed no clear difference in radiological failure compared with sealapex (eugenol-free calcium hydroxide); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6 and 12 months
RR 0.20 [0.01, 3.92]
1 study · 40 participants
GRADE not reported

Vitapex (calcium hydroxide/iodoform) vs ZOE + calcium hydroxide + iodoform (MPRCF, unnamed product)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) led to higher clinical failure compared with ZOE + calcium hydroxide + iodoform (MPRCF, unnamed product); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 21.79 [1.32, 360.78]
1 study · 109 participants
GRADE not reported

Vitapex (calcium hydroxide/iodoform) vs Sealapex (eugenol-free calcium hydroxide)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with sealapex (eugenol-free calcium hydroxide); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 0.20 [0.01, 3.92]
1 study · 40 participants
GRADE not reported

Metapex (calcium hydroxide/iodoform) vs Calcium hydroxide (CH)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide/iodoform (CH/iodoform) showed no clear difference in clinical failure compared with calcium hydroxide (CH); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.13 [0.82, 1.54]
1 study · 65 participants
GRADE not reported

Metapex (calcium hydroxide/iodoform) vs Calcium hydroxide (CH)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide/iodoform (CH/iodoform) showed no clear difference in radiological failure compared with calcium hydroxide (CH); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.17 [0.87, 1.59]
1 study · 65 participants
GRADE not reported

Calcium hydroxide (CH) vs Formocresol (FC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) probably leads to higher radiological failure compared with formocresol (FC) (moderate certainty).

2 findings from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.86 [1.42, 2.44]
6 studies · 332 participants
Moderate
Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
24 months
RR 3.11 [1.61, 6.02]
1 study · 120 participants
Low

Calcium hydroxide (CH) vs Formocresol (FC)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) may leads to higher clinical failure compared with formocresol (FC) (low certainty).

2 findings from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
24 months
RR 3.83 [1.68, 8.74]
1 study · 120 participants
Low
Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.87 [1.22, 2.89]
6 studies · 332 participants
Moderate

Calcium hydroxide (CH) vs Ferric sulphate (FS)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) showed no clear difference in radiological failure compared with ferric sulphate (FS) (low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.28 [0.53, 3.13]
2 studies · 122 participants
Low

Calcium hydroxide (CH) vs Ferric sulphate (FS)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) showed no clear difference in clinical failure compared with ferric sulphate (FS) (low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 3.41 [0.37, 31.61]
2 studies · 122 participants
Low

Calcium hydroxide (CH) vs Portland cement (PC)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) showed no clear difference in clinical failure compared with portland cement (PC); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 and 24 months
RR 13.00 [0.80, 212.02]
1 study · 30 participants
GRADE not reported

Calcium hydroxide (CH) vs Mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) showed no clear difference in clinical failure compared with mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 3.00 [0.13, 70.92]
1 study · 62 participants
GRADE not reported

Calcium hydroxide (CH) vs Portland cement (PC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) led to higher radiological failure compared with portland cement (PC); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 17.00 [1.07, 270.41]
1 study · 30 participants
GRADE not reported

Calcium hydroxide (CH) vs Zinc oxide and eugenol (ZOE)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) showed no clear difference in clinical failure compared with zinc oxide and eugenol (ZOE); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 9.00 [0.52, 156.92]
1 study · 40 participants
GRADE not reported

Calcium hydroxide (CH) vs Mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) led to higher radiological failure compared with mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 8.00 [1.06, 60.21]
1 study · 62 participants
GRADE not reported