Findings

What do systematic reviews say?

26 questions · 27 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 21 · 77.8%Very low 1 · 3.7%Low 3 · 11.1%Moderate 2 · 7.4%High 0 · 0%

Calcium hydroxide (CH) vs Formocresol (FC)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) may leads to higher clinical failure compared with formocresol (FC) (low certainty).

2 findings from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
24 months
RR 3.83 [1.68, 8.74]
1 study · 120 participants
Low
Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.87 [1.22, 2.89]
6 studies · 332 participants
Moderate

Calcium hydroxide (CH) vs Ferric sulphate (FS)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) showed no clear difference in clinical failure compared with ferric sulphate (FS) (low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 3.41 [0.37, 31.61]
2 studies · 122 participants
Low

Calcium hydroxide (CH) vs Portland cement (PC)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) showed no clear difference in clinical failure compared with portland cement (PC); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 and 24 months
RR 13.00 [0.80, 212.02]
1 study · 30 participants
GRADE not reported

Calcium hydroxide (CH) vs Mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) showed no clear difference in clinical failure compared with mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 3.00 [0.13, 70.92]
1 study · 62 participants
GRADE not reported

Calcium hydroxide (CH) vs Zinc oxide and eugenol (ZOE)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) showed no clear difference in clinical failure compared with zinc oxide and eugenol (ZOE); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 9.00 [0.52, 156.92]
1 study · 40 participants
GRADE not reported

Calcium hydroxide cement (Dycal) vs Calcium sulphate hemihydrate (DentoGen)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether calcium hydroxide cement (Dycal) changes clinical failure compared with calcium sulphate hemihydrate (DentoGen) (very low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 4.00 [0.49, 32.72]
1 study · 40 participants
Very low

Metapex (calcium hydroxide/iodoform) vs Zinc oxide and propolis (ZOP)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Metapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with zinc oxide and propolis (ZOP); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 2.00 [0.20, 19.91]
1 study · 32 participants
GRADE not reported

Metapex (calcium hydroxide/iodoform) vs Endoflas chlorophenol free (Endoflas-CF)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Metapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with endoflas chlorophenol free (Endoflas-CF); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.00 [0.16, 6.25]
1 study · 32 participants
GRADE not reported

Vitapex (calcium hydroxide/iodoform) vs 3Mix (ciprofloxacin + metronidazole + minocycline)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with 3Mix (ciprofloxacin + metronidazole + minocycline); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.00 [0.07, 15.12]
1 study · 50 participants
GRADE not reported

Metapex (calcium hydroxide/iodoform) vs Endoflas (CH + ZOE + iodoform)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Metapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with endoflas (CH + ZOE + iodoform); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6 months
RR 0.33 [0.01, 7.58]
2 studies · 92 participants
GRADE not reported

Vitapex (calcium hydroxide/iodoform) vs Zinc oxide and eugenol (ZOE)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) may leads to higher clinical failure compared with zinc oxide and eugenol (ZOE) (low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 4.75 [1.21, 18.55]
4 studies · 161 participants
Low

Vitapex (calcium hydroxide/iodoform) vs Calcium hydroxide (CH)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with calcium hydroxide (CH); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 0.11 [0.01, 1.94]
1 study · 40 participants
GRADE not reported

Metapex (calcium hydroxide/iodoform) vs Zinc oxide and eugenol (ZOE)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Metapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with zinc oxide and eugenol (ZOE) (moderate certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 0.71 [0.15, 3.33]
2 studies · 62 participants
Moderate

Vitapex (calcium hydroxide/iodoform) vs ZOE + calcium hydroxide + iodoform (MPRCF, unnamed product)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) led to higher clinical failure compared with ZOE + calcium hydroxide + iodoform (MPRCF, unnamed product); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 21.79 [1.32, 360.78]
1 study · 109 participants
GRADE not reported

Vitapex (calcium hydroxide/iodoform) vs RC Fill

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6, 12 and 30 months
No clinical failure in any participant at 6/12/30 months (Pramila 2016); not estimable
1 study · 86 participants
GRADE not reported

Vitapex (calcium hydroxide/iodoform) vs Sealapex (eugenol-free calcium hydroxide)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with sealapex (eugenol-free calcium hydroxide); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 0.20 [0.01, 3.92]
1 study · 40 participants
GRADE not reported

Glutaraldehyde + calcium hydroxide (CH) vs Full strength formocresol (FC)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Glutaraldehyde + calcium hydroxide (CH) showed no clear difference in clinical failure compared with full strength formocresol (FC); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
3 months
RR 1.10 [0.17, 7.10]
1 study · 44 participants
GRADE not reported

Glutaraldehyde + calcium hydroxide (CH) vs Glutaraldehyde + zinc oxide and eugenol (ZOE)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Glutaraldehyde + calcium hydroxide (CH) showed no clear difference in clinical failure compared with glutaraldehyde + zinc oxide and eugenol (ZOE); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 2.90 [0.32, 26.38]
1 study · 61 participants
GRADE not reported

Metapex (calcium hydroxide/iodoform) vs Full strength formocresol (FC)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide/iodoform (CH/iodoform) led to higher clinical failure compared with full strength formocresol (FC); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 9.11 [3.04, 27.31]
1 study · 67 participants
GRADE not reported

Metapex (calcium hydroxide/iodoform) vs Calcium hydroxide (CH)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide/iodoform (CH/iodoform) showed no clear difference in clinical failure compared with calcium hydroxide (CH); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.13 [0.82, 1.54]
1 study · 65 participants
GRADE not reported