CPP-ACP vs No active treatment (control)
Enamel surface microhardness · Extracted human teeth with early/artificial enamel lesions (in vitro)
In vitro, CPP-ACP significantly increased enamel surface microhardness versus control (SMD 2.07, 95% CI 1.24 to 2.89; ungraded).
2 findings from 1 review
- Evaluation of the efficacy of casein phosphopeptide-amorphous calcium phosphate on remineralization of white spot… 2019 All outcomes6 hours to 30 days · In vitro (extracted human teeth)SMD 2.07 [1.24, 2.89]8 studies · 170 participantsGRADE not reported
- Evaluation of the efficacy of casein phosphopeptide-amorphous calcium phosphate on remineralization of white spot… 2019 All outcomes5 to 7 days · In vitro (extracted human teeth) · Knoop microhardnessSMD 3.52 [2.68, 4.36]3 studies · 64 participantsGRADE not reported