Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Headline outcomes only

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No studies found 2 · 28.6%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 2 · 28.6%High 2 · 28.6%

COX‐2 NSAIDs vs placebo

BASDAI Scale from 0 to 100 (higher is worse) · patients with axSpA (AS and nr‐axSpA)

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and… 2015 · Cochrane Headline outcomes only
no estimate extracted
193 participants
Moderate

COX‐2 NSAIDs vs placebo

BASFI Scale from 0 to 100 (higher is worse) · patients with axSpA (AS and nr‐axSpA)

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and… 2015 · Cochrane Headline outcomes only
no estimate extracted
349 participants
High

COX‐2 NSAIDs vs placebo

BASMI Scale from 0 to 10 (higher is worse) · patients with axSpA (AS and nr‐axSpA)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

COX‐2 NSAIDs vs placebo

Radiographic progression · patients with axSpA (AS and nr‐axSpA)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

COX‐2 NSAIDs vs placebo

Number of serious adverse events · patients with axSpA (AS and nr‐axSpA)

COX‐2 NSAIDs showed no clear difference in number of serious adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and… 2015 · Cochrane Headline outcomes only
RR 0.92 [0.14, 6.21]
669 participants
Moderate

COX‐2 NSAIDs vs placebo

Pain (short term) WOMAC scale from 0 to 20 points (higher is worse pain). · patients with axSpA (AS and nr‐axSpA)

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and… 2015 · Cochrane Headline outcomes only
no estimate extracted
349 participants
High

COX‐2 NSAIDs vs placebo

Withdrawals due to adverse events · patients with axSpA (AS and nr‐axSpA)

COX‐2 NSAIDs showed no clear difference in withdrawals due to adverse events compared with placebo (low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and… 2015 · Cochrane Headline outcomes only
RR 2.14 [0.36, 12.56]
669 participants
Low