Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 1 · 50%Very low 0 · 0%Low 0 · 0%Moderate 1 · 50%High 0 · 0%

CLOZAPINE vs Typical antipsychotics

Adverse effects 1. Blood problems · patients with schizophrenia

CLOZAPINE showed no clear difference in adverse effects 1. Blood problems compared with TYPICAL ANTIPSYCHOTICS; GRADE not reported.

1 finding from 1 review

Clozapine versus typical neuroleptic medication for schizophrenia 2009 · Cochrane Headline outcomes only
RR 1.9 [0.97, 3.71]
5 studies · 827 participants
GRADE not reported

CLOZAPINE vs Typical antipsychotics

Adverse effects: 1. Blood problems ‐ decreased white cell count · patients with schizophrenia

CLOZAPINE probably leads to higher adverse effects: 1. Blood problems ‐ decreased white cell count compared with TYPICAL ANTIPSYCHOTICS ‐ OVERALL (moderate certainty).

1 finding from 1 review

Clozapine versus typical neuroleptic medication for schizophrenia 2009 · Cochrane Headline outcomes only
RR 7.09 [1.96, 25.62]
13 studies · 1031 participants
Moderate