Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

25 questions · 25 findings · 4 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 15 · 60%Low 4 · 16%Moderate 6 · 24%High 0 · 0%

CHLORPROMAZINE vs RESERPINE

Functioning: not improved occupational adjustment (short term) · patients with schizophrenia

CHLORPROMAZINE showed no clear difference in functioning: not improved occupational adjustment (short term) compared with RESERPINE (moderate certainty).

1 finding from 1 review

CHLORPROMAZINE vs RESERPINE

Adverse events ‐ toxic reaction (short term) · patients with schizophrenia

CHLORPROMAZINE showed no clear difference in adverse events ‐ toxic reaction (short term) compared with RESERPINE (moderate certainty).

1 finding from 1 review

CHLORPROMAZINE vs RESERPINE

Leaving the study early ‐ due to adverse effects (short term) · patients with schizophrenia

CHLORPROMAZINE showed no clear difference in leaving the study early ‐ due to adverse effects (short term) compared with RESERPINE (moderate certainty).

1 finding from 1 review

CHLORPROMAZINE LOW DOSE (≤ 400 mg/day) vs MEDIUM DOSE (401 mg/day to 800 mg/day)

Global state: no improvement ‐ short term · patients with schizophrenia

It is very uncertain whether CHLORPROMAZINE LOW DOSE (≤ 400 mg/day) changes global state: no improvement ‐ short term compared with MEDIUM DOSE (401 mg/day to 800 mg/day) (very low certainty).

1 finding from 1 review

CHLORPROMAZINE LOW DOSE (≤ 400 mg/day) vs MEDIUM DOSE (401 mg/day to 800 mg/day)

Adverse effects: any observed extrapyramidal symptoms ‐ short term (up to 6 months) · patients with schizophrenia

CHLORPROMAZINE LOW DOSE (≤ 400 mg/day) probably leads to lower adverse effects: extrapyramidal symptoms (unspecified extrapyramidal… compared with MEDIUM DOSE (401 mg/day to 800 mg/day) (moderate certainty).

1 finding from 1 review