Findings

What do systematic reviews say?

8 questions · 8 findings · 2 reviews · Drugs and Alcohol

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 25%Low 6 · 75%Moderate 0 · 0%High 0 · 0%

Abstinence · cannabis dependence

Buspirone showed no clear difference in participants abstinent at end of treatment compared with placebo (low certainty).

1 finding from 1 review

Pharmacotherapies for cannabis dependence 2019 · Cochrane Headline outcomes only
RR 1.98 [0.62, 6.33]
1 study · 175 participants
Low

Participants with at least some Side Effects · cannabis dependence

Buspirone showed no clear difference in participants experiencing adverse effects compared with placebo (low certainty).

1 finding from 1 review

Pharmacotherapies for cannabis dependence 2019 · Cochrane Headline outcomes only
RR 1.14 [1, 1.29]
2 studies · 225 participants
Low

Withdrawals due to adverse events · cannabis dependence

Buspirone showed no clear difference in participants withdrawn due to adverse effects compared with placebo (low certainty).

1 finding from 1 review

Pharmacotherapies for cannabis dependence 2019 · Cochrane Headline outcomes only
RR 0.63 [0.15, 2.6]
2 studies · 225 participants
Low

Completion of scheduled treatment · cannabis dependence

Buspirone showed no clear difference in completion of scheduled treatment compared with placebo (low certainty).

1 finding from 1 review

Pharmacotherapies for cannabis dependence 2019 · Cochrane Headline outcomes only
RR 0.96 [0.74, 1.23]
2 studies · 225 participants
Low

Benzodiazepine discontinuation, end of intervention · adults who withdraw from chronic benzodiazepine use

Buspirone showed no clear difference in benzodiazepine discontinuation, end of intervention compared with placebo (low certainty).

1 finding from 1 review

Benzodiazepine discontinuation, longest · adults who withdraw from chronic benzodiazepine use

Buspirone showed no clear difference in benzodiazepine discontinuation, longest compared with placebo (low certainty).

1 finding from 1 review

Benzodiazepine withdrawal symptoms, end of intervention · adults who withdraw from chronic benzodiazepine use

1 finding from 1 review

Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Very low

Benzodiazepine withdrawal symptoms, longest · adults who withdraw from chronic benzodiazepine use

1 finding from 1 review

Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 15 participants
Very low