Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

20 questions · 20 findings · 4 reviews

No studies found 3 · 15%GRADE not reported 6 · 30%Very low 3 · 15%Low 8 · 40%Moderate 0 · 0%High 0 · 0%

Buspirone vs placebo

Abstinence · cannabis dependence

Buspirone showed no clear difference in participants abstinent at end of treatment compared with placebo (low certainty).

1 finding from 1 review

Buspirone vs placebo

Participants with at least some Side Effects · cannabis dependence

Buspirone showed no clear difference in participants experiencing adverse effects compared with placebo (low certainty).

1 finding from 1 review

Buspirone vs placebo

Withdrawals due to adverse events · cannabis dependence

Buspirone showed no clear difference in participants withdrawn due to adverse effects compared with placebo (low certainty).

1 finding from 1 review

Buspirone vs placebo

Completion of scheduled treatment · cannabis dependence

Buspirone showed no clear difference in completion of scheduled treatment compared with placebo (low certainty).

1 finding from 1 review

Buspirone vs placebo

Short‐term (within 1 month) change in isolated movement, objective and subjective measures of speech production Cooper 2008 reported 3 speech measures: ICARS speech subscale. Scale from: 0 to 8. Higher scores indicate greater clinical severity Syl... · people with speech disorder resulting from hereditary ataxias
1 finding from 1 review

Buspirone vs placebo

Tardive dyskinesia: No clinically important improvement · psychiatric patients (schizophrenia) with antipsychotic‐induced tardive dyskinesia

ANXIOLYTIC ‐ BUSPIRONE may leads to lower tardive dyskinesia: No clinically important improvement compared with PLACEBO (low certainty).

1 finding from 1 review

Buspirone vs placebo

Leaving the study early · psychiatric patients (schizophrenia) with antipsychotic‐induced tardive dyskinesia

It is very uncertain whether ANXIOLYTIC ‐ BUSPIRONE changes acceptability of treatment (measured by participants leaving the… compared with PLACEBO (very low certainty).

1 finding from 1 review

Buspirone vs placebo

Social confidence, social inclusion, social networks, or personalised quality of life ‐ not reported · psychiatric patients (schizophrenia) with antipsychotic‐induced tardive dyskinesia

The review found no eligible studies for this question.

1 finding from 1 review