Findings

What do systematic reviews say?

5 questions · 5 findings · 2 reviews · Tobacco Addiction

No studies found 1 · 20%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 80%Moderate 0 · 0%High 0 · 0%

Biochemically validated smoking cessation at the latest point in pregnancy (20 weeks' gestation or more) · Pregnant women who smoke

Bupropion showed no clear difference in biochemically validated smoking cessation at the latest point in… compared with control (low certainty).

1 finding from 1 review

Pharmacological interventions for promoting smoking cessation during pregnancy 2020 · Cochrane Headline outcomes only
RR 0.74 [0.21, 2.64]
2 studies · 76 participants
Low

Mean birthweight · Pregnant women who smoke

Bupropion showed no clear difference in mean birthweight (g) compared with control (low certainty).

1 finding from 1 review

Pharmacological interventions for promoting smoking cessation during pregnancy 2020 · Cochrane Headline outcomes only
MD 122.64
2 studies · 68 participants
Low

Miscarriage and spontaneous abortion · Pregnant women who smoke

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for promoting smoking cessation during pregnancy 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Bupropion versus placebo All biochemically validated · smokers with current depression

Bupropion showed no clear difference in bupropion versus placebo All biochemically validated compared with control (low certainty).

1 finding from 1 review

Smoking cessation interventions for smokers with current or past depression 2013 · Cochrane Headline outcomes only
RR 1.37 [0.83, 2.27]
5 studies · 410 participants
Low

Bupropion versus placebo Biochemical validation (majority) and self report · patients with smokers with past depression

Bupropion may leads to higher bupropion versus placebo Biochemical validation (majority) and self… compared with control (low certainty).

1 finding from 1 review

Smoking cessation interventions for smokers with current or past depression 2013 · Cochrane Headline outcomes only
RR 2.04 [1.31, 3.18]
4 studies · 404 participants
Low