Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Neonatal

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No studies found 1 · 16.7%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 66.7%Moderate 1 · 16.7%High 0 · 0%

Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP)

Treatment failure · preterm infants receiving nasal CPAP

Bubble may leads to lower treatment failure compared with ventilator or Infant Flow Driver nasal continuous positive airway… (low certainty).

1 finding from 1 review

Bubble devices versus other pressure sources for nasal continuous positive airway pressure in preterm infants 2023 · Cochrane Headline outcomes only
RR 0.76 [0.6, 0.95]
13 studies · 1230 participants
Low

Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP)

Mortality before hospital discharge · preterm infants receiving nasal CPAP

Bubble showed no clear difference in all‐cause mortality before hospital discharge compared with ventilator or Infant Flow Driver nasal continuous positive airway… (low certainty).

1 finding from 1 review

Bubble devices versus other pressure sources for nasal continuous positive airway pressure in preterm infants 2023 · Cochrane Headline outcomes only
RR 0.93 [0.64, 1.36]
10 studies · 1189 participants
Low

Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP)

Neurodevelopmental disability · preterm infants receiving nasal CPAP

The review found no eligible studies for this question.

1 finding from 1 review

Bubble devices versus other pressure sources for nasal continuous positive airway pressure in preterm infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP)

Pneumothorax · preterm infants receiving nasal CPAP

Bubble showed no clear difference in pneumothorax compared with ventilator or Infant Flow Driver nasal continuous positive airway… (low certainty).

1 finding from 1 review

Bubble devices versus other pressure sources for nasal continuous positive airway pressure in preterm infants 2023 · Cochrane Headline outcomes only
RR 0.73 [0.4, 1.34]
14 studies · 1340 participants
Low

Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP)

Moderate‐severe nasal injury · preterm infants receiving nasal CPAP

Bubble probably leads to higher moderate‐severe nasal injury compared with ventilator or Infant Flow Driver nasal continuous positive airway… (moderate certainty).

1 finding from 1 review

Bubble devices versus other pressure sources for nasal continuous positive airway pressure in preterm infants 2023 · Cochrane Headline outcomes only
RR 2.29 [1.37, 3.82]
8 studies · 753 participants
Moderate

Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP)

Bronchopulmonary dysplasia · preterm infants receiving nasal CPAP

Bubble showed no clear difference in bronchopulmonary dysplasia compared with ventilator or Infant Flow Driver nasal continuous positive airway… (low certainty).

1 finding from 1 review

Bubble devices versus other pressure sources for nasal continuous positive airway pressure in preterm infants 2023 · Cochrane Headline outcomes only
RR 0.76 [0.53, 1.1]
7 studies · 603 participants
Low