What do systematic reviews say?

Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP)

Bubble showed no clear difference in pneumothorax compared with ventilator or Infant Flow Driver nasal continuous positive airway… (low certainty).

• Bubble devices versus other pressure sources for nasal continuous positive airway pressure in preterm infants 2023 · Cochrane Headline outcomes only
  RR 0.73 [0.4, 1.34]
  14 studies · 1340 participants
  Low