Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 0 · 0%Moderate 1 · 50%High 0 · 0%

Botulinum toxin type A vs other established prophylactic agent

Number experiencing adverse effects · adults with migraine

It is very uncertain whether botulinum toxin type A changes total number of participants experiencing an adverse event compared with other established prophylactic agent (very low certainty).

1 finding from 1 review

Botulinum toxins for the prevention of migraine in adults 2018 · Cochrane Headline outcomes only
RR 0.76 [0.59, 0.98]
2 studies · 114 participants
Very low

Botulinum toxin type A vs placebo

Number experiencing adverse effects · adults with migraine

Botulinum toxin type A probably leads to higher total number of participants experiencing an adverse event compared with placebo (moderate certainty).

1 finding from 1 review

Botulinum toxins for the prevention of migraine in adults 2018 · Cochrane Headline outcomes only
RR 1.28 [1.12, 1.47]
13 studies · 3325 participants
Moderate