Botulinum neurotoxin B vs placebo
Overall cervical dystonia improvement as · adults with cervical dystonia
1 finding from 1 review
- no estimate extracted3 studies · 316 participantsModerate
Findings
What do systematic reviews say?
7 questions · 7 findings · 1 reviews
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 14.3%Low 2 · 28.6%Moderate 1 · 14.3%High 3 · 42.9%
Botulinum neurotoxin B vs placebo
Withdrawals due to adverse events · adults with cervical dystonia
Botulinum neurotoxin B showed no clear difference in proportion of withdrawals due to adverse events compared with placebo (low certainty).
1 finding from 1 review
- RR 0.88 [0.19, 4.06]4 studies · 440 participantsLow
Botulinum neurotoxin B vs placebo
Cervical dystonia‐specific pain · adults with cervical dystonia
1 finding from 1 review
- no estimate extracted2 studies · 207 participantsLow
Botulinum neurotoxin B vs placebo
Subjective change as assessed by the patient at week 4 · adults with cervical dystonia
1 finding from 1 review
- no estimate extracted3 studies · 316 participantsHigh
Botulinum neurotoxin B vs placebo
Proportion of participants with adverse events · adults with cervical dystonia
It is very uncertain whether botulinum neurotoxin B changes proportion of participants with adverse events compared with placebo (very low certainty).
1 finding from 1 review
- RR 1.09 [0.97, 1.23]2 studies · 186 participantsVery low
Botulinum neurotoxin B vs placebo
Adverse effects: dry mouth · adults with cervical dystonia
Botulinum neurotoxin B leads to higher adverse events: dry mouth compared with placebo (high certainty).
1 finding from 1 review
- RR 7.65 [2.75, 21.32]4 studies · 438 participantsHigh
Botulinum neurotoxin B vs placebo
Dysphagia · adults with cervical dystonia
Botulinum neurotoxin B leads to higher adverse events: dysphagia compared with placebo (high certainty).
1 finding from 1 review
- RR 6.78 [2.42, 19.05]4 studies · 438 participantsHigh