Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 25%Low 1 · 25%Moderate 0 · 0%High 2 · 50%

Botulinum neurotoxin B vs placebo

Adverse effects: dry mouth · adults with cervical dystonia

Botulinum neurotoxin B leads to higher adverse events: dry mouth compared with placebo (high certainty).

1 finding from 1 review

Botulinum toxin type B for cervical dystonia 2016 · Cochrane Headline outcomes only
RR 7.65 [2.75, 21.32]
4 studies · 438 participants
High

Botulinum neurotoxin B vs placebo

Dysphagia · adults with cervical dystonia

Botulinum neurotoxin B leads to higher adverse events: dysphagia compared with placebo (high certainty).

1 finding from 1 review

Botulinum toxin type B for cervical dystonia 2016 · Cochrane Headline outcomes only
RR 6.78 [2.42, 19.05]
4 studies · 438 participants
High

Botulinum neurotoxin B vs placebo

Proportion of participants with adverse events · adults with cervical dystonia

It is very uncertain whether botulinum neurotoxin B changes proportion of participants with adverse events compared with placebo (very low certainty).

1 finding from 1 review

Botulinum toxin type B for cervical dystonia 2016 · Cochrane Headline outcomes only
RR 1.09 [0.97, 1.23]
2 studies · 186 participants
Very low

Botulinum neurotoxin B vs placebo

Withdrawals due to adverse events · adults with cervical dystonia

Botulinum neurotoxin B showed no clear difference in proportion of withdrawals due to adverse events compared with placebo (low certainty).

1 finding from 1 review

Botulinum toxin type B for cervical dystonia 2016 · Cochrane Headline outcomes only
RR 0.88 [0.19, 4.06]
4 studies · 440 participants
Low