Findings

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6 questions · 7 findings · 1 reviews · Stroke

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 28.6%High 5 · 71.4%

Blood pressure‐lowering drugs (BPLDs) vs placebo or no treatment

Recurrent stroke of any type · stroke and/or TIA

Blood pressure‐lowering drugs (BPLDs) probably leads to lower recurrent stroke of any type compared with placebo or no treatment (moderate certainty).

2 findings from 1 review

Blood pressure‐lowering treatment for preventing recurrent stroke, major vascular events, and dementia in patients… 2018 · Cochrane Headline outcomes only
RR 0.81 [0.7, 0.93]
8 studies · 35110 participants
Moderate
Blood pressure‐lowering treatment for preventing recurrent stroke, major vascular events, and dementia in patients… 2018 · Cochrane Headline outcomes only
HR 0.82 [0.65, 1.03]
3 studies · 26889 participants
High

Blood pressure‐lowering drugs (BPLDs) vs placebo or no treatment

Stroke, myocardial infarction, or vascular death · stroke and/or TIA

Blood pressure‐lowering drugs (BPLDs) showed no clear difference in major vascular event (composite of non‐fatal stroke, non‐fatal… compared with placebo or no treatment (high certainty).

1 finding from 1 review

Blood pressure‐lowering treatment for preventing recurrent stroke, major vascular events, and dementia in patients… 2018 · Cochrane Headline outcomes only
RR 0.9 [0.78, 1.04]
4 studies · 28630 participants
High

Blood pressure‐lowering drugs (BPLDs) vs placebo or no treatment

Myocardial infarction · stroke and/or TIA

Blood pressure‐lowering drugs (BPLDs) showed no clear difference in myocardial infarction compared with placebo or no treatment (high certainty).

1 finding from 1 review

Blood pressure‐lowering treatment for preventing recurrent stroke, major vascular events, and dementia in patients… 2018 · Cochrane Headline outcomes only
RR 0.9 [0.72, 1.11]
6 studies · 34747 participants
High

Blood pressure‐lowering drugs (BPLDs) vs placebo or no treatment

Deaths due to vascular events · stroke and/or TIA

Blood pressure‐lowering drugs (BPLDs) leads to lower vascular death compared with placebo or no treatment (high certainty).

1 finding from 1 review

Blood pressure‐lowering treatment for preventing recurrent stroke, major vascular events, and dementia in patients… 2018 · Cochrane Headline outcomes only
RR 0.85 [0.76, 0.95]
6 studies · 34747 participants
High

Blood pressure‐lowering drugs (BPLDs) vs placebo or no treatment

Death by any cause · stroke and/or TIA

Blood pressure‐lowering drugs (BPLDs) showed no clear difference in death by any cause compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Blood pressure‐lowering treatment for preventing recurrent stroke, major vascular events, and dementia in patients… 2018 · Cochrane Headline outcomes only
RR 0.98 [0.91, 1.05]
8 studies · 35110 participants
Moderate

Blood pressure‐lowering drugs (BPLDs) vs placebo or no treatment

Dementia · stroke and/or TIA

Blood pressure‐lowering drugs (BPLDs) showed no clear difference in dementia compared with placebo or no treatment (high certainty).

1 finding from 1 review

Blood pressure‐lowering treatment for preventing recurrent stroke, major vascular events, and dementia in patients… 2018 · Cochrane Headline outcomes only
RR 0.88 [0.73, 1.06]
2 studies · 6671 participants
High