Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Hypertension

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 40%Moderate 3 · 60%High 0 · 0%

Total mortality

Beta‐blockers showed no clear difference in total mortality compared with renin‐angiotensin system inhibitors (moderate certainty).

1 finding from 1 review

Beta‐blockers for hypertension 2017 · Cochrane Headline outcomes only
RR 1.1 [0.98, 1.24]
3 studies · 10828 participants
Moderate

Total cardiovascular disease

Beta‐blockers showed no clear difference in total cardiovascular disease compared with renin‐angiotensin system inhibitors (low certainty).

1 finding from 1 review

Beta‐blockers for hypertension 2017 · Cochrane Headline outcomes only
RR 1 [0.72, 1.38]
3 studies · 10828 participants
Low

Stroke

Beta‐blockers probably leads to higher total stroke compared with renin‐angiotensin system inhibitors (moderate certainty).

1 finding from 1 review

Beta‐blockers for hypertension 2017 · Cochrane Headline outcomes only
RR 1.3 [1.11, 1.53]
2 studies · 9951 participants
Moderate

Total coronary heart disease

Beta‐blockers showed no clear difference in total coronary heart disease compared with renin‐angiotensin system inhibitors (low certainty).

1 finding from 1 review

Beta‐blockers for hypertension 2017 · Cochrane Headline outcomes only
RR 0.9 [0.76, 1.06]
2 studies · 9951 participants
Low

Withdrawals due to adverse events

Beta‐blockers probably leads to higher withdrawal due to adverse effect compared with renin‐angiotensin system inhibitors (moderate certainty).

1 finding from 1 review

Beta‐blockers for hypertension 2017 · Cochrane Headline outcomes only
RR 1.41 [1.29, 1.54]
2 studies · 9951 participants
Moderate