Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%

Beta‐blockers vs placebo, no treatment or surveillance only

Congestive heart failure · people with confirmed diagnosis of Marfan syndrome

Beta‐blockers showed no clear difference in congestive heart failure compared with placebo, no treatment or surveillance only (low certainty).

1 finding from 1 review

Beta‐blockers for preventing aortic dissection in Marfan syndrome 2017 · Cochrane Headline outcomes only
RR 1.19 [0.18, 7.96]
1 study · 70 participants
Low

Beta‐blockers vs placebo, no treatment or surveillance only

Clinically important non‐fatal end point as defined byShores 1994(aortic dissection, aortic regurgitation, congestive heart failure, or cardiovascular surgery) · people with confirmed diagnosis of Marfan syndrome

Beta‐blockers showed no clear difference in clinically important non‐fatal end point as defined byShores… compared with placebo, no treatment or surveillance only (low certainty).

1 finding from 1 review

Beta‐blockers for preventing aortic dissection in Marfan syndrome 2017 · Cochrane Headline outcomes only
RR 0.79 [0.37, 1.69]
1 study · 70 participants
Low