Findings

What do systematic reviews say?

5 questions · 5 findings · 4 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 60%Moderate 1 · 20%High 1 · 20%

Beta‐blockers vs placebo, no treatment or surveillance only

All‐cause mortality · people with confirmed diagnosis of Marfan syndrome

Beta‐blockers showed no clear difference in all‐cause mortality compared with placebo, no treatment or surveillance only (low certainty).

1 finding from 1 review

Beta‐blockers for preventing aortic dissection in Marfan syndrome 2017 · Cochrane Headline outcomes only
RR 0.24 [0.01, 4.75]
1 study · 70 participants
Low

Beta‐blockers vs placebo or no treatment

All‐cause mortality (RR) · patients with chronic heart failure with preserved ejection fraction

Beta‐blockers showed no clear difference in all‐cause mortality (RR) compared with placebo or no treatment (low certainty).

1 finding from 1 review

Beta‐blockers and inhibitors of the renin‐angiotensin aldosterone system for chronic heart failure with preserved… 2021 · Cochrane Headline outcomes only
RR 0.82 [0.67, 1]
4 studies · 1105 participants
Low

Beta‐blockers vs placebo or no intervention

All‐cause mortality maximum · patients with suspected or diagnosed myocardial infarction

Beta‐blockers probably leads to lower all‐cause mortality at maximum compared with placebo or no intervention (moderate certainty).

1 finding from 1 review

Beta‐blockers for suspected or diagnosed acute myocardial infarction 2019 · Cochrane Headline outcomes only
RR 0.93 [0.86, 0.99]
21 studies · 25210 participants
Moderate

Beta‐blockers vs placebo or no intervention

All‐cause mortality at 'less than 3 months' · patients with suspected or diagnosed myocardial infarction

Beta‐blockers showed no clear difference in all‐cause mortality at 'less than 3 months' compared with placebo or no intervention (high certainty).

1 finding from 1 review

Beta‐blockers for suspected or diagnosed acute myocardial infarction 2019 · Cochrane Headline outcomes only
RR 0.94 [0.9, 1]
46 studies · 80452 participants
High

Perioperative beta‐blockers vs placebo or usual care

Early all‐cause mortality (within 30 days) · adults undergoing non‐cardiac surgery under general anaesthesia (to include: low‐risk, medium‐risk, and high‐risk surgeries)

Perioperative beta‐blockers showed no clear difference in early all‐cause mortality (within 30 days) compared with placebo or standard care (low certainty).

1 finding from 1 review

Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing non‐cardiac… 2019 · Cochrane Headline outcomes only
RR 1.17 [0.89, 1.54]
16 studies · 11446 participants
Low