Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 100%High 0 · 0%

LABA/LAMA vs LABA plus inhaled corticosteroid (ICS)

SGRQ total score change from baseline (≥ 4 points, MCID) · stable COPD

Long‐acting muscarinic antagonist (LAMA) plus long‐acting… showed no clear difference in SGRQ total score change from baseline (≥ 4 points, MCID) compared with LABA plus inhaled corticosteroid (ICS) (moderate certainty).

1 finding from 1 review

Long‐acting muscarinic antagonist (LAMA) plus long‐acting beta‐agonist (LABA) versus LABA plus inhaled corticosteroid… 2023 · Cochrane Headline outcomes only
OR 1.06 [0.9, 1.25]
4 studies · 13614 participants
Moderate