Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Oral Health

Sort:Best matchNewest Highest certainty Download CSV

No studies found 1 · 16.7%GRADE not reported 2 · 33.3%Very low 3 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Autologous platelet concentrates (APC) + enamel matrix derivative (EMD) vs EMD (enamel matrix derivative) alone

Change in radiographic bone defect filling (RBF) (%) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + enamel matrix derivative… changes change in radiographic bone defect filling (RBF) (%) compared with EMD (enamel matrix derivative) alone (very low certainty).

1 finding from 1 review

Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
All follow-ups
MD -0.60 [-6.21, 5.01]
1 study · 49 participants
Very low

Autologous platelet concentrates (APC) + enamel matrix derivative (EMD) vs EMD (enamel matrix derivative) alone

Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + enamel matrix derivative… changes change in clinical attachment level (CAL) (mm) compared with EMD (enamel matrix derivative) alone (very low certainty).

1 finding from 1 review

Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
All follow-ups
MD 0.10 [-0.13, 0.32]
2 studies · 75 participants
Very low

Autologous platelet concentrates (APC) + enamel matrix derivative (EMD) vs EMD (enamel matrix derivative) alone

Pocket closure (complete pocket closure) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

1 finding from 1 review

Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
No complete pocket closure was reported (outcome addressed across included studies; no usable comparative estimate).
Studies not reported
GRADE not reported

Autologous platelet concentrates (APC) + enamel matrix derivative (EMD) vs EMD (enamel matrix derivative) alone

Oral health-related quality of life · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

The review found no eligible studies for this question.

1 finding from 1 review

Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
No quantitative analysis regarding patients' quality of life was possible (no data).
0 studies
No studies found

Autologous platelet concentrates (APC) + enamel matrix derivative (EMD) vs EMD (enamel matrix derivative) alone

Change in probing pocket depth (PPD) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + enamel matrix derivative… changes change in probing depth (PD) (mm) compared with EMD (enamel matrix derivative) alone (very low certainty).

1 finding from 1 review

Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
All follow-ups
MD 0.13 [-0.05, 0.30]
2 studies · 75 participants
Very low

Autologous platelet concentrates (APC) + enamel matrix derivative (EMD) vs EMD (enamel matrix derivative) alone

Tooth survival · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

1 finding from 1 review

Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
All studies in all groups reported a survival rate of 100% for the treated teeth (no comparative estimate; not GRADE-rated).
2 studies
GRADE not reported