Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Airways

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 28.6%Moderate 4 · 57.1%High 1 · 14.3%

As‐required FABA/ICS inhalers vs regular inhaled steroid

Inhaled steroid dose · mild asthma

1 finding from 1 review

Combination fixed‐dose beta agonist and steroid inhaler as required for adults or children with mild asthma 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 7180 participants
Moderate

As‐required FABA/ICS inhalers vs as‐required FABA inhalers

Inhaled steroid dose · mild asthma

1 finding from 1 review

Combination fixed‐dose beta agonist and steroid inhaler as required for adults or children with mild asthma 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2554 participants
Moderate

As‐required FABA/ICS inhalers vs regular inhaled steroid

Total systemic steroid dose · mild asthma

1 finding from 1 review

Combination fixed‐dose beta agonist and steroid inhaler as required for adults or children with mild asthma 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1330 participants
Moderate

As‐required FABA/ICS inhalers vs regular inhaled steroid

Adverse events · mild asthma

As‐required FABA/ICS inhalers showed no clear difference in adverse events compared with regular inhaled steroid (moderate certainty).

1 finding from 1 review

Combination fixed‐dose beta agonist and steroid inhaler as required for adults or children with mild asthma 2021 · Cochrane Headline outcomes only
OR 0.96 [0.82, 1.14]
4 studies · 8072 participants
Moderate

As‐required FABA/ICS inhalers vs regular inhaled steroid

Rate of exacerbations requiring systemic corticosteroids · mild asthma

As‐required FABA/ICS inhalers showed no clear difference in exacerbations requiring systemic steroid compared with regular inhaled steroid (low certainty).

1 finding from 1 review

Combination fixed‐dose beta agonist and steroid inhaler as required for adults or children with mild asthma 2021 · Cochrane Headline outcomes only
OR 0.79 [0.59, 1.07]
4 studies · 8065 participants
Low

As‐required FABA/ICS inhalers vs regular inhaled steroid

Hospital admission, ED and urgent care visits · mild asthma

As‐required FABA/ICS inhalers may leads to lower hospital admission, ED and urgent care visits compared with regular inhaled steroid (low certainty).

1 finding from 1 review

Combination fixed‐dose beta agonist and steroid inhaler as required for adults or children with mild asthma 2021 · Cochrane Headline outcomes only
OR 0.63 [0.44, 0.91]
4 studies · 8065 participants
Low

As‐required FABA/ICS inhalers vs regular inhaled steroid

Asthma control · mild asthma

1 finding from 1 review

Combination fixed‐dose beta agonist and steroid inhaler as required for adults or children with mild asthma 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 7382 participants
High