Findings

What do systematic reviews say?

10 questions · 10 findings · 1 reviews · Eyes and Vision

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No studies found 1 · 10%GRADE not reported 0 · 0%Very low 7 · 70%Low 2 · 20%Moderate 0 · 0%High 0 · 0%

Any intervention vs steroid alone or plus levofloxacin

Resolution of symptoms · epidemic keratoconjunctivitis

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Any intervention vs steroid alone or plus levofloxacin

Proportion of participants with resolution of signs within 7 days of treatment (higher is favored) · epidemic keratoconjunctivitis

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Any intervention vs steroid alone or plus levofloxacin

Proportion of participants in whose eyes SEI had disappeared within 21 days of treatment (higher is favored) · epidemic keratoconjunctivitis

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Any intervention vs steroid alone or plus levofloxacin

Proportion of participants who discontinued medication and did not develop rebound SEI within 21 days (higher is favored) · epidemic keratoconjunctivitis

It is very uncertain whether any intervention changes proportion of participants who discontinued medication and did not… compared with steroid alone or plus levofloxacin (very low certainty).

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
RR 1.04 [0.94, 1.14]
3 studies · 231 participants
Very low

Any intervention vs steroid alone or plus levofloxacin

Proportion of participants who had evidence of adenoviral eradication within 14 days of treatment (higher is favored) · epidemic keratoconjunctivitis

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Any intervention vs artificial tears or saline

Resolution of symptoms · epidemic keratoconjunctivitis

Any intervention may leads to higher proportion of participants with resolution of symptoms within 10… compared with artificial tears or saline (low certainty).

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
RR 1.15 [1.07, 1.24]
2 studies · 409 participants
Low

Any intervention vs artificial tears or saline

Proportion of participants with resolution of signs within 10 days of treatment (higher is favored) · epidemic keratoconjunctivitis

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
3.19 [2.29, 4.45]
2 studies · 409 participants
Low

Any intervention vs artificial tears or saline

Proportion of participants in whose eyes SEI had disappeared within 21 days of treatment (higher is favored) · epidemic keratoconjunctivitis

It is very uncertain whether any intervention changes proportion of participants in whose eyes SEI had disappeared within… compared with artificial tears or saline (very low certainty).

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
RR 1.34 [0.88, 2.04]
2 studies · 156 participants
Very low

Any intervention vs artificial tears or saline

Proportion of participants who discontinued medication and did not develop rebound SEI within 21 days (higher is favored) · epidemic keratoconjunctivitis

The review found no eligible studies for this question.

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Any intervention vs artificial tears or saline

Proportion of participants who had evidence of adenoviral eradication within 14 days of treatment (higher is favored) · epidemic keratoconjunctivitis

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low