Global impression ‐ need for additional medication ‐ medium term Number of participants requiring additional medication · psychosis‐induced aggression or agitation
1 finding from 1 review
Adverse effects/events ‐ extrapyramidal symptoms ‐ medium term Number of instances of extrapyramidal symptoms · psychosis‐induced aggression or agitation
Benzodiazepines + antipsychotics showed no clear difference in adverse effects/events: extrapyramidal symptoms ‐ +/vs haloperidol ‐… compared with same antipsychotics (low certainty).
1 finding from 1 review
Satisfaction with treatment: from the perspective of consumer, family and informal carers or professionals/carers at any point during the acute management stage · psychosis‐induced aggression or agitation
1 finding from 1 review
Cost‐effectiveness · psychosis‐induced aggression or agitation
1 finding from 1 review
Adverse effects: 1. Sedation · psychosis‐induced aggression or agitation
1 finding from 1 review
Global state: no improvement ‐ medium termAs defined in each study · psychosis‐induced aggression or agitation
1 finding from 1 review
Global state: need for additional medication ‐ medium term · psychosis‐induced aggression or agitation
1 finding from 1 review
Adverse effects/events ‐ extrapyramidal symptoms ‐ medium term Number of instances of extrapyramidal symptoms · psychosis‐induced aggression or agitation
1 finding from 1 review
Satisfaction with treatment: from the perspective of consumer, family and informal carers or professionals/carers at any point during the acute management stage · psychosis‐induced aggression or agitation
1 finding from 1 review
Cost‐effectiveness · psychosis‐induced aggression or agitation
1 finding from 1 review
Tranquillisation or asleep: sedation ‐ medium termNumber of participants sedated · psychosis‐induced aggression or agitation
It is very uncertain whether benzodiazepines plus antipsychotics changes tranquillisation or asleep: sedation ‐ medium termNumber of… compared with antihistamines plus antipsychotics (very low certainty).
1 finding from 1 review
Global state: no improvement ‐ medium termAs defined in each study · psychosis‐induced aggression or agitation
It is very uncertain whether benzodiazepines plus antipsychotics changes global state: no improvement ‐ medium termAs defined in each study compared with antihistamines plus antipsychotics (very low certainty).
1 finding from 1 review
Global impression ‐ need for additional medication ‐ medium term Number of participants requiring additional medication · psychosis‐induced aggression or agitation
1 finding from 1 review
Adverse effects/events ‐ extrapyramidal symptoms ‐ medium term Number of instances of extrapyramidal symptoms · psychosis‐induced aggression or agitation
It is very uncertain whether benzodiazepines plus antipsychotics changes adverse effects/events: extrapyramidal symptoms ‐ medium termNumber… compared with antihistamines plus antipsychotics (very low certainty).
1 finding from 1 review
Satisfaction with treatment: from the perspective of consumer, family and informal carers or professionals/carers at any point during the acute management stage · psychosis‐induced aggression or agitation
1 finding from 1 review
Cost‐effectiveness · psychosis‐induced aggression or agitation
1 finding from 1 review
Response to treatment clinically relevant response as defined by the authors · schizophrenia
Adjunctive lithium + antipsychotics may leads to higher response to treatment clinically relevant response as defined by the… compared with placebo/no adjunctive treatment + antipsychotics (low certainty).
1 finding from 1 review
Acceptability ‐ total dropouts · schizophrenia
It is very uncertain whether adjunctive lithium + antipsychotics changes acceptability of treatment leaving early due to any reason compared with placebo/no adjunctive treatment + antipsychotics (very low certainty).
1 finding from 1 review
> 50% reduction in depressive symptoms · schizophrenia
Adjunctive lithium + antipsychotics showed no clear difference in clinically significant response on depressive symptoms at least 50%… compared with placebo/no adjunctive treatment + antipsychotics (low certainty).
1 finding from 1 review
Clinically significant response on manic symptoms at least 50% Bech‐Rafaelsen improvement · schizophrenia
Adjunctive lithium + antipsychotics showed no clear difference in clinically significant response on manic symptoms at least 50%… compared with placebo/no adjunctive treatment + antipsychotics (low certainty).
1 finding from 1 review