Findings

What do systematic reviews say?

3 questions · 4 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 25%Low 3 · 75%Moderate 0 · 0%High 0 · 0%

Antioestrogen vs antioestrogen

Clinical pregnancy rate · ovulation induction in polycystic ovarian syndrome

It is very uncertain whether antioestrogen changes clomiphene citrate plus tamoxifen versus clomiphene citrate ‐… compared with antioestrogen (very low certainty).

2 findings from 1 review

Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
OR 3.32 [0.12, 91.6]
1 study · 20 participants
Very low
Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
OR 1.3 [0.92, 1.85]
5 studies · 757 participants
Low

Antioestrogen vs placebo

Clinical pregnancy rate · ovulation induction in polycystic ovarian syndrome

Antioestrogen may leads to higher clinical pregnancy rate compared with placebo (low certainty).

1 finding from 1 review

Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
OR 5.91 [1.77, 19.68]
3 studies · 133 participants
Low

Antioestrogen plus medical adjunct vs antioestrogen

Clinical pregnancy · ovulation induction in polycystic ovarian syndrome

Antioestrogen plus medical adjunct showed no clear difference in clomiphene citrate plus bromocriptine versus clomiphene citrate ‐… compared with antioestrogen alone (low certainty).

1 finding from 1 review

Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
OR 1.03 [0.48, 2.21]
2 studies · 174 participants
Low