Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

168 questions · 181 findings · 19 reviews

No studies found 63 · 34.8%GRADE not reported 49 · 27.1%Very low 39 · 21.5%Low 14 · 7.7%Moderate 11 · 6.1%High 5 · 2.8%

Antimicrobial lozenge vs placebo

Dry mouth (xerostomia) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region

Antimicrobial lozenge showed no clear difference in xerostomia compared with placebo; GRADE not reported.

1 finding from 1 review

Antimicrobial lozenge vs placebo

Quality of life and other oral related symptoms · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
1 finding from 1 review

Antimicrobial lozenge vs placebo

Side effects (other: dryness in mouth, diarrhoea, constipation) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
1 finding from 1 review

Antimicrobial coolant A (chlorhexidine) vs povidone‐iodine

Reduction in level of contamination in aerosols (CFU): chlorhexidine vs povidone iodine coolant during ultrasonic scaling · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether antimicrobial coolant A (chlorhexidine) changes reduction in level of contamination in aerosols (CFU): chlorhexidine… compared with antimicrobial coolant B (povidone iodine) (very low certainty).

1 finding from 1 review

Antimicrobial coolant A (chlorhexidine) vs Antimicrobial coolant B (cinnamon extract)

Reduction in level of contamination in aerosols (CFU): chlorhexidine vs cinnamon extract coolant during ultrasonic scaling · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether antimicrobial coolant A (chlorhexidine) changes reduction in level of contamination in aerosols (CFU): chlorhexidine… compared with antimicrobial coolant B (cinnamon extract) (very low certainty).

1 finding from 1 review

Impregnated catheters vs antiseptic‐coated catheter

Symptomatic CAUTI: without microbiological evidence ‐ antibiotic versus silver alloy · Patients with an indwelling urethral catheter of short‐term duration

Antimicrobial‐impregnated catheter showed no clear difference in symptomatic CAUTI: without microbiological evidence ‐ antibiotic… compared with antiseptic‐coated catheter (moderate certainty).

1 finding from 1 review

Impregnated catheters vs antiseptic‐coated catheter

Symptomatic CAUTI: with microbiological evidence ‐ antibiotic versus silver alloy · Patients with an indwelling urethral catheter of short‐term duration

Antimicrobial‐impregnated catheter leads to lower symptomatic CAUTI: with microbiological evidence ‐ antibiotic versus… compared with antiseptic‐coated catheter (high certainty).

1 finding from 1 review

Impregnated catheters vs antiseptic‐coated catheter

Patient discomfort whilst catheter is in situ · Patients with an indwelling urethral catheter of short‐term duration

Antimicrobial‐impregnated catheter leads to higher patient discomfort whilst catheter is in situ compared with antiseptic‐coated catheter (high certainty).

1 finding from 1 review