Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

7 questions · 7 findings · 1 reviews · ENT

No studies found 2 · 28.6%GRADE not reported 0 · 0%Very low 0 · 0%Low 5 · 71.4%Moderate 0 · 0%High 0 · 0%

Antihistamines vs scopolamine

Physiological measures: core temperature and gastric tachyarrhythmia (electrogastrography) · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs acupuncture

Physiological measures: heart rate, core temperature and gastric tachyarrhythmia (electrogastrography) · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs placebo

Adverse effects: 1. Sedation · patients with motion sickness

Antihistamines may leads to higher adverse effects: sedation Assessed by: adverse effect questionnaire… compared with placebo (low certainty).

1 finding from 1 review

Antihistamines vs placebo

Adverse effects: impaired cognition Assessed by: adverse effect questionnaire (presence or absence given numerical values) · patients with motion sickness

Antihistamines showed no clear difference in adverse effects: impaired cognition Assessed by: adverse effect… compared with placebo (low certainty).

1 finding from 1 review

Antihistamines vs placebo

Adverse effects ‐ Blurred vision No of patients with blurred vision · patients with motion sickness

Antihistamines showed no clear difference in adverse effects: blurred vision Assessed by: adverse effect… compared with placebo (low certainty).

1 finding from 1 review