Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

72 questions · 74 findings · 7 reviews

No studies found 19 · 25.7%GRADE not reported 3 · 4.1%Very low 34 · 45.9%Low 18 · 24.3%Moderate 0 · 0%High 0 · 0%

Tricyclic antidepressants vs placebo

Benzodiazepine discontinuation, end of intervention · adults who withdraw from chronic benzodiazepine use

It is very uncertain whether tricyclic antidepressants changes benzodiazepine discontinuation, end of intervention compared with placebo (very low certainty).

1 finding from 1 review

Tricyclic antidepressants vs another medication

Treatment response (post‐treatment score on self report and clinician‐rated scales) · somatoform disorders in adults

Tricyclic antidepressants showed no clear difference in treatment response (post‐treatment score on self report and… compared with another medication (low certainty).

1 finding from 1 review