Findings

What do systematic reviews say?

5 questions · 5 findings · 4 reviews

Sort:Best matchNewest Highest certainty Download CSV

No studies found 2 · 40%GRADE not reported 0 · 0%Very low 1 · 20%Low 0 · 0%Moderate 2 · 40%High 0 · 0%

Antidepressants vs placebo

Adverse events: death ‐ at end of treatment (Analysis 1.14) · people with stroke

It is very uncertain whether pharmacological interventions (antidepressants) changes adverse events: death ‐ at end of treatment Analysis 1.12 compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological, psychological and non‐invasive brain stimulation interventions for preventing depression after stroke 2020 · Cochrane Headline outcomes only
RR 1.25 [0.32, 4.91]
9 studies · 496 participants
Very low

Antidepressants vs any other pharmacological intervention

Adverse events · women of any age, with PND up to 12 months

The review found no eligible studies for this question.

1 finding from 1 review

Antidepressant treatment for postnatal depression 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antidepressants vs placebo

Non‐serious adverse events Timing of outcome assessment: end of treatment · patients with borderline personality disorder

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for people with borderline personality disorder 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antidepressants vs placebo

Adverse events ‐ Withdrawn for medical reasons · patients with depression during opioid agonist treatment for opioid dependence

Antidepressants probably leads to higher adverse events ‐ Withdrawn for medical reasons compared with placebo (moderate certainty).

1 finding from 1 review

Pharmacological treatment for depression during opioid agonist treatment for opioid dependence 2010 · Cochrane Headline outcomes only
RR 3.03 [1.2, 7.68]
3 studies · 276 participants
Moderate

Antidepressants vs placebo according to any definition

Adverse events ‐ Withdrawn for medical reasons · patients with depression during opioid agonist treatment for opioid dependence

Antidepressants probably leads to higher adverse events ‐ Withdrawn for medical reasons compared with placebo according to any definition (moderate certainty).

1 finding from 1 review

Pharmacological treatment for depression during opioid agonist treatment for opioid dependence 2010 · Cochrane Headline outcomes only
RR 2.9 [1.23, 6.86]
4 studies · 311 participants
Moderate