Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Common Mental Disorders

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%

Antidepressants vs placebo at 12 months' follow‐up

Recurrence · older people in remission from depression

Antidepressant medication may leads to lower recurrence at 12 months compared with placebo at 12 months' follow‐up (low certainty).

1 finding from 1 review

Continuation and maintenance treatments for depression in older people 2016 · Cochrane Headline outcomes only
RR 0.67 [0.55, 0.82]
3 studies · 247 participants
Low

Antidepressants vs placebo at 12 months' follow‐up

Overall drop‐out rates (excluding deaths) at 12 months · older people in remission from depression

Antidepressant medication showed no clear difference in overall drop‐out rates (excluding deaths) at 12 months compared with placebo at 12 months' follow‐up (low certainty).

1 finding from 1 review

Continuation and maintenance treatments for depression in older people 2016 · Cochrane Headline outcomes only
RR 1.48 [0.75, 2.92]
1 study · 121 participants
Low