Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

103 questions · 109 findings · 11 reviews

No studies found 20 · 18.3%GRADE not reported 4 · 3.7%Very low 12 · 11%Low 35 · 32.1%Moderate 28 · 25.7%High 10 · 9.2%

Anticoagulant vs placebo or no intervention

Clinically relevant non‐major bleeding Treatment duration 28 ‐ 42 days · people with distal DVT

Anticoagulant leads to higher clinically relevant non‐major bleeding ( compared with no intervention or placebo (high certainty).

1 finding from 1 review

Higher‐dose anticoagulants vs lower‐dose anticoagulants

Necessity for additional respiratory support · people hospitalised with COVID‐19

It is very uncertain whether higher‐dose anticoagulants changes necessity for additional respiratory support compared with lower‐dose anticoagulants (very low certainty).

1 finding from 1 review