Findings

What do systematic reviews say?

8 questions · 8 findings · 1 reviews · Gut

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No studies found 2 · 25%GRADE not reported 2 · 25%Very low 4 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Antibiotics plus probiotics vs placebo or no intervention

Failure to induce clinical remission at end of study · people with active UC

It is very uncertain whether antibiotics plus probiotics changes failure to induce clinical remission at end of study compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Antibiotics for the induction and maintenance of remission in ulcerative colitis 2022 · Cochrane Headline outcomes only
RR 0.68 [0.39, 1.19]
2 studies · 98 participants
Very low

Antibiotics plus probiotics vs placebo or no intervention

Failure to induce clinical response at end of study · people with active UC

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for the induction and maintenance of remission in ulcerative colitis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics plus probiotics vs placebo or no intervention

Serious adverse events · people with active UC

It is very uncertain whether antibiotics plus probiotics changes serious adverse events compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Antibiotics for the induction and maintenance of remission in ulcerative colitis 2022 · Cochrane Headline outcomes only
RR 1 [0.07, 15.08]
2 studies · 98 participants
Very low

Antibiotics plus probiotics vs placebo or no intervention

Withdrawals due to adverse events · people with active UC

It is very uncertain whether antibiotics plus probiotics changes withdrawals due to adverse events compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Antibiotics for the induction and maintenance of remission in ulcerative colitis 2022 · Cochrane Headline outcomes only
RR 1 [0.07, 15.08]
2 studies · 98 participants
Very low

Antibiotics vs probiotic

Failure to induce clinical remission at end of study · people with active UC

It is very uncertain whether antibiotics changes failure to induce clinical remission at end of study compared with probiotics (very low certainty).

1 finding from 1 review

Antibiotics for the induction and maintenance of remission in ulcerative colitis 2022 · Cochrane Headline outcomes only
RR 0.47 [0.23, 0.94]
1 study · 50 participants
Very low

Antibiotics vs probiotic

Failure to induce clinical response at end of study · people with active UC

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for the induction and maintenance of remission in ulcerative colitis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs probiotic

Serious adverse events · people with active UC

1 finding from 1 review

Antibiotics for the induction and maintenance of remission in ulcerative colitis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
GRADE not reported

Antibiotics vs probiotic

Withdrawals due to adverse events · people with active UC

1 finding from 1 review

Antibiotics for the induction and maintenance of remission in ulcerative colitis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
GRADE not reported