Findings

What do systematic reviews say?

7 questions · 7 findings · 5 reviews

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No studies found 5 · 71.4%GRADE not reported 0 · 0%Very low 1 · 14.3%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%

Hyperbaric oxygen therapy plus standard care (surgery, antibiotics, oral rinse) vs Standard care alone (surgery, antibiotics, oral rinse)

Adverse effects · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating bisphosphonate‐related osteonecrosis of the jaw (BRONJ) 2016 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Systemic antibiotics alone vs systematic antibiotics plus antibiotic lock solution

Adverse effects · patients on maintenance HD with CRBSI

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating catheter‐related bloodstream infections in people receiving maintenance haemodialysis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs placebo or usual care

Number of women with adverse effects · postpartum breastfeeding women

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing mastitis after childbirth 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs topical treatments

Number of women with adverse effects · postpartum breastfeeding women

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing mastitis after childbirth 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Systemic antibiotics plus antibiotic lock solutions plus tissue plasminogen activator vs systemic antibiotics plus antibiotic lock solutions plus heparin

Adverse effects · patients on maintenance HD with CRBSI

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating catheter‐related bloodstream infections in people receiving maintenance haemodialysis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral plus nebulised antibiotics vs oral antibiotics plus nebulised placebo

Adverse effects of treatment · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen

Oral plus nebulised antibiotics showed no clear difference in adverse effects of treatment compared with oral antibiotics plus nebulised placebo (low certainty).

1 finding from 1 review

Interventions for the eradication of meticillin‐resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis 2022 · Cochrane Headline outcomes only
OR 3 [0.11, 79.91]
1 study · 29 participants
Low

Combined HBO and perioperative antibiotics prior to dental implant therapy vs antibiotics alone

Adverse effects (including quality of life) · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)

1 finding from 1 review

Interventions for preventing osteoradionecrosis of the jaws in adults receiving head and neck radiotherapy 2019 · Cochrane All outcomes
1 year
This comparison was only made in 1 study which reported no serious adverse events associated with HBO therapy. Quality of life measures (oral status, functioning, satisfaction) showed emotional functioning and pain…
1 study · 26 participants
Very low