What do systematic reviews say?

Antibiotic prophylaxis vs no treatment

• Antibiotic prophylaxis for episiotomy repair following vaginal birth 2017 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Antibiotic prophylaxis before dental procedure vs placebo or no prophylaxis

The review found no eligible studies for this question.

• Antibiotic prophylaxis for preventing bacterial endocarditis following dental procedures 2022 · Cochrane All outcomes
  Adverse effects of antibiotics | No data reported | 248 (1 study) | - | -
  0 studies
  No studies found

Antibiotic prophylaxis vs no treatment or placebo

It is very uncertain whether routine antibiotic prophylaxis changes adverse effects of antibiotics (skin rash) compared with no treatment or placebo (very low certainty).

• Routine antibiotic prophylaxis after normal vaginal birth for reducing maternal infectious morbidity 2017 · Cochrane Headline outcomes only
  RR 3.03 [0.32, 28.95]
  2 studies · 1706 participants
  Very low

Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs placebo

It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes adverse effects compared with placebo (very low certainty).

• Antibiotics to prevent complications following tooth extractions 2021 · Cochrane All outcomes

  1st to 7th day
  RR 1.46 [0.81, 2.64]
  8 studies · 1277 participants
  Very low