Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

888 questions · 936 findings · 109 reviews

No studies found 196 · 20.9%GRADE not reported 88 · 9.4%Very low 226 · 24.1%Low 217 · 23.2%Moderate 152 · 16.2%High 57 · 6.1%

Antibiotics vs placebo

Discontinuation of medication due to adverse events · adults with renal vasculitis for maintenance therapy

Antibiotics showed no clear difference in adverse events causing study drug discontinuation compared with placebo (low certainty).

1 finding from 1 review

Antibiotics vs placebo

Urinary tract infection · adults with renal vasculitis for maintenance therapy

Antibiotics may leads to lower infection (urinary tract infection) compared with placebo (low certainty).

1 finding from 1 review

Antibiotics vs placebo or no treatment

Clinical treatment failure (Persistent or worsening symptoms at the end of treatment) · patients symptomatic for NTS infection

It is very uncertain whether antibiotics changes clinical treatment failure (Persistent or worsening symptoms at the… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Antibiotics vs placebo or no treatment

Diarrhoea · patients symptomatic for NTS infection

It is very uncertain whether antibiotics changes presence of diarrhoea at 2‐4 days compared with placebo or no treatment (very low certainty).

2 findings from 1 review