Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Airways

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 33.3%Moderate 4 · 66.7%High 0 · 0%

PEF (L/min) · patients with adults with acute asthma

Aminophylline showed no clear difference in PEF (L/min) ‐ at 60 min compared with placebo (low certainty).

1 finding from 1 review

Hospital admissions · patients with adults with acute asthma

Aminophylline showed no clear difference in hospital admissions compared with placebo (moderate certainty).

1 finding from 1 review

Addition of intravenous aminophylline to inhaled beta₂‐agonists in adults with acute asthma 2012 · Cochrane Headline outcomes only
OR 0.58 [0.3, 1.12]
6 studies · 315 participants
Moderate

Tremor · patients with adults with acute asthma

Aminophylline showed no clear difference in tremor compared with placebo (low certainty).

1 finding from 1 review

Vomiting · patients with adults with acute asthma

Aminophylline probably leads to higher vomiting compared with placebo (moderate certainty).

1 finding from 1 review

Addition of intravenous aminophylline to inhaled beta₂‐agonists in adults with acute asthma 2012 · Cochrane Headline outcomes only
OR 4.21 [2.2, 8.07]
7 studies · 321 participants
Moderate

Arrhythmia/palpitations · patients with adults with acute asthma

Aminophylline probably leads to higher arrhythmia/palpitations compared with placebo (moderate certainty).

1 finding from 1 review

Addition of intravenous aminophylline to inhaled beta₂‐agonists in adults with acute asthma 2012 · Cochrane Headline outcomes only
OR 3.02 [1.15, 7.9]
6 studies · 249 participants
Moderate

Convulsions · patients with adults with acute asthma

1 finding from 1 review

Addition of intravenous aminophylline to inhaled beta₂‐agonists in adults with acute asthma 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Moderate