Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews

No studies found 4 · 57.1%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 28.6%Moderate 1 · 14.3%High 0 · 0%

Acute gout attacks · people with chronic gout

Allopurinol showed no clear difference in acute gout attacks compared with benzbromarone (low certainty).

1 finding from 1 review

Allopurinol for chronic gout 2014 · Cochrane Headline outcomes only
RR 0.28 [0.01, 6.58]
1 study · 55 participants
Low

Proportion achieving target serum urate · people with chronic gout

Allopurinol showed no clear difference in proportion achieving target serum urate compared with benzbromarone (moderate certainty).

1 finding from 1 review

Allopurinol for chronic gout 2014 · Cochrane Headline outcomes only
RR 0.79 [0.56, 1.11]
2 studies · 101 participants
Moderate

Pain reduction ‐ not measured · people with chronic gout

The review found no eligible studies for this question.

1 finding from 1 review

Allopurinol for chronic gout 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Function ‐ not measured · people with chronic gout

The review found no eligible studies for this question.

1 finding from 1 review

Allopurinol for chronic gout 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tophus regression ‐ not measured · people with chronic gout

The review found no eligible studies for this question.

1 finding from 1 review

Allopurinol for chronic gout 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Withdrawals due to adverse events · people with chronic gout

Allopurinol showed no clear difference in withdrawal due to adverse events compared with benzbromarone (low certainty).

1 finding from 1 review

Allopurinol for chronic gout 2014 · Cochrane Headline outcomes only
RR 0.8 [0.18, 3.58]
2 studies · 91 participants
Low

Serious adverse effects · people with chronic gout

The review found no eligible studies for this question.

1 finding from 1 review

Allopurinol for chronic gout 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found