What do systematic reviews say?

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

All psychological therapies showed no clear difference in short‐term remission compared with antidepressants alone or antidepressants and benzodiazepines (low certainty).

• Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
  RR 0.86 [0.71, 1.05]
  11 studies · 663 participants
  Low

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

All psychological therapies showed no clear difference in short‐term response compared with antidepressants alone or antidepressants and benzodiazepines (low certainty).

• Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
  RR 0.95 [0.76, 1.18]
  12 studies · 800 participants
  Low

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

It is very uncertain whether all psychological therapies changes dropouts for any reason compared with antidepressants alone or antidepressants and benzodiazepines (very low certainty).

• Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
  RR 1.08 [0.77, 1.51]
  13 studies · 909 participants
  Very low

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

• Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

• Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 638 participants
  Low