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Evidence found and GRADE certainty

13 questions · 14 findings · 1 reviews · Skin

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 7.1%Moderate 9 · 64.3%High 4 · 28.6%

Adalimumab weekly vs placebo

Frequency of serious adverse effects · participants with hidradenitis suppurativa

Adalimumab weekly showed no clear difference in frequency of serious adverse effects compared with placebo (moderate certainty).

1 finding from 1 review

Adalimumab weekly vs placebo

Treatment discontinuation · participants with hidradenitis suppurativa

Adalimumab weekly showed no clear difference in frequency of treatment discontinuation compared with placebo (moderate certainty).

1 finding from 1 review

Adalimumab weekly vs placebo

Proportion of participants with infectious adverse effects · participants with hidradenitis suppurativa

Adalimumab weekly showed no clear difference in proportion of participants with infectious adverse effects compared with placebo (moderate certainty).

1 finding from 1 review

Adalimumab weekly vs placebo

Proportion with improvement in pain VAS · participants with hidradenitis suppurativa

Adalimumab weekly probably leads to higher proportion with improvement in pain VAS compared with placebo (moderate certainty).

1 finding from 1 review

Adalimumab every other week vs placebo

Treatment discontinuation · participants with hidradenitis suppurativa

Adalimumab every other week showed no clear difference in frequency of treatment discontinuation compared with placebo (high certainty).

1 finding from 1 review

Adalimumab every other week vs placebo

Proportion of participants with infectious adverse effects · participants with hidradenitis suppurativa

Adalimumab every other week showed no clear difference in proportion of participants with infectious adverse effects compared with placebo (high certainty).

1 finding from 1 review

Adalimumab every other week vs placebo

Proportion with improvement in pain · participants with hidradenitis suppurativa

Adalimumab every other week showed no clear difference in proportion with improvement in pain compared with placebo (moderate certainty).

1 finding from 1 review

Adalimumab every other week vs placebo

Frequency of serious adverse effects · participants with hidradenitis suppurativa

Adalimumab every other week showed no clear difference in frequency of serious adverse effects compared with placebo (high certainty).

1 finding from 1 review