What do systematic reviews say?

Acupoint PC6 stimulation vs sham

Acupoint PC6 stimulation may leads to lower nausea ‐ All trials compared with sham (low certainty).

• Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting 2015 · Cochrane Headline outcomes only
  RR 0.68 [0.6, 0.77]
  40 studies · 4742 participants
  Low

Acupoint PC6 stimulation vs sham

Acupoint PC6 stimulation may leads to lower vomiting ‐ All trials compared with sham (low certainty).

• Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting 2015 · Cochrane Headline outcomes only
  RR 0.6 [0.51, 0.71]
  45 studies · 5147 participants
  Low

Acupoint PC6 stimulation vs sham

Acupoint PC6 stimulation may leads to lower rescue antiemetics compared with sham (low certainty).

• Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting 2015 · Cochrane Headline outcomes only
  RR 0.64 [0.55, 0.73]
  39 studies · 4622 participants
  Low

Acupoint PC6 stimulation vs sham

• Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting 2015 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 35 participants
  GRADE not reported

Acupoint PC6 stimulation vs antiemetics

Acupoint PC6 stimulation showed no clear difference in nausea ‐ All antiemetics combined compared with antiemetic drug (moderate certainty).

• Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting 2015 · Cochrane Headline outcomes only
  RR 0.91 [0.75, 1.1]
  14 studies · 1332 participants
  Moderate

Acupoint PC6 stimulation vs antiemetics

Acupoint PC6 stimulation showed no clear difference in vomiting ‐ All antiemetics combined compared with antiemetic drug (moderate certainty).

• Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting 2015 · Cochrane Headline outcomes only
  RR 0.93 [0.74, 1.17]
  19 studies · 1708 participants
  Moderate

Acupoint PC6 stimulation vs antiemetics

Acupoint PC6 stimulation showed no clear difference in rescue antiemetic compared with antiemetic drug (moderate certainty).

• Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting 2015 · Cochrane Headline outcomes only
  RR 0.87 [0.65, 1.16]
  9 studies · 895 participants
  Moderate

Acupoint PC6 stimulation vs antiemetics

• Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 11 participants
  GRADE not reported

Acupoint PC6 stimulation and antiemetic combination vs antiemetics

It is very uncertain whether acupoint PC6 stimulation and antiemetic combination changes vomiting compared with antiemetic (very low certainty).

• Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting 2015 · Cochrane Headline outcomes only
  RR 0.56 [0.35, 0.91]
  9 studies · 687 participants
  Very low

Acupoint PC6 stimulation and antiemetic combination vs antiemetics

Acupoint PC6 stimulation and antiemetic combination may leads to lower rescue antiemetic compared with antiemetic (low certainty).

• Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting 2015 · Cochrane Headline outcomes only
  RR 0.61 [0.44, 0.86]
  5 studies · 419 participants
  Low

Acupoint PC6 stimulation and antiemetic combination vs antiemetics

• Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting 2015 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 7 participants
  GRADE not reported

Acupoint PC6 stimulation and antiemetic combination vs antiemetics

It is very uncertain whether acupoint PC6 stimulation and antiemetic combination changes nausea compared with antiemetic (very low certainty).

• Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting 2015 · Cochrane Headline outcomes only
  RR 0.79 [0.55, 1.13]
  8 studies · 642 participants
  Very low